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Table 1 Ends of PM in the literature (short)

From: What is personalized medicine: sharpening a vague term based on a systematic literature review

Ends in (1459)

1 Research (156)

C. Therapy (975)

A. Basic research (43)

Diagnosis (68)

On causes and processes of diseases (9)

   unspecified (18)

On risk factors for diseases (3)

   tailored diagnosis/diagnostics (28)

On disease classification (18)

   improved diagnosis/diagnostic measures (22)

To further the development of new treatment measures (13)

   unspecified (10)

   effectiveness/efficacy (5)

B. Research on new diagnostic and prognostic/predictive measures (30)

   timing (6)

   tailored diagnostics (1)

Unspecified (10)

Prognosis/Prediction (158)

Regarding tailoring (2)

   unspecified (4)

Regarding stratification (4)

   prediction of disease progression/recurrence (5)

Regarding improved diagnostic/prognostic/ predictive measures (9)

   predictive information guiding clinical decision making (21)

   unspecified (2)

   prediction of treatment effects/effectiveness (60)

   effectiveness (6)

   efficiency (1)

   tailoring prognosis/prediction (39)

Regarding companion diagnostics (5)

   stratification by predicted treatment effects (25)

C. Research on new therapeutic measures (83)

   improvement of prognostic/predictive measures (4)

Unspecified (15)

   unspecified (2)

Regarding tailoring (15)

   safety (1)

Regarding stratification (40)

   effectiveness/efficacy (1)

Regarding improved treatment measures (13)

Treatment (749)

   unspecified (5)

   unspecified (27)

   safety (3)

   choice of therapeutic measure (104)

   effectiveness (3)

   regarding treatment monitoring (12)

   efficiency (2)

   effectiveness/efficacy of treatment (16)

 

   efficiency of treatment (2)

2 Drug approval (14)

   safety of treatment (6)

A. Improved validation processes (1)

   treatment outcomes (2)

B. Improved clinical trials (11)

   tailoring therapy/therapeutic measures (269)

Unspecified (4)

Efficiency (7)

   stratified therapeutic measure (18)

C. Improved approval processes (2)

   improvement of therapy/therapeutic measures (293)

 

   unspecified (41)

3 Health care (1202)

   choice of treatment (32)

A. Health care in general (69)

   effectiveness/efficacy (92)

Unspecified (1)

   efficiency (2)

Decision making in health care (3)

   timing (4)

Tailoring health care (37)

   safety (83)

Improved health care (28)

   tailoring treatment measures (39)

   unspecified (17)

 

   effectiveness/efficacy (1)

4 Improved health (10)

   efficiency (2)

 

   safety (2)

5 Further ends (77)

   choices in health care (1)

Unspecified (11)

   tailoring health care (5)

(Tailored) patient management (3)

B. Prevention (158)

Stratification (1)

Risk prognosis/prediction (82)

Reduce/control costs (30)

   unspecified (52)

Improved effectiveness/efficacy (24)

   at the individual level (26)

Improved timing (1)

   at the population level (3)

Improved safety (3)

   improved risk prognosis/prediction (1)

Improved quality of life (4)

Primary prevention (76)

 

   unspecified (34)

 

   tailoring preventive measures (22)

 

   stratified preventive measures (1)

 

   improved prevention/preventive strategies (19)

 

   unspecified (16)

 

   effectiveness (1)

 

   timing (2)