Table 2 Means of PM in the literature (short)
From: What is personalized medicine: sharpening a vague term based on a systematic literature review
Means in (1025) | |
|---|---|
1 Research (97) | genetic information (417) |
A. On individual differences (4) | unspecified (19) |
B. On genetics/genomics (39) | regarding knowledge of genes/genetic variation (215) |
Unspecified (11) | regarding gene expression (13) |
Regarding the influence of genes on disease development/progression (5) | regarding genomics/genomic variation (98) |
Regarding the influence of genes on drug response (22) | regarding the transcriptome (4) |
regarding DNA/RNA(6) | |
Regarding the interaction of genes with other factors that influence disease development/progression (1) | regarding epigenetics (8) |
regarding gene-environment interaction (4) | |
C. On further factors that influence disease progression/development (8) | regarding pharmacogenetics/pharmacogenomics (41) |
D. On further factors that influence drug response (4) | regarding further points (9) |
information on proteomics (35) | |
E. On biomarkers (40) | information on metabolomics (14) |
F. On new technologies (2) | Further points mentioned (6) |
B. Usage of environmental factors/information (33) | |
2 Application in patient care (928) | C. Usage of further individual factors/information (126) |
A. Usage of clinical information/clinical indicators (718) | Unspecified (77) |
Age-related information (4) | |
Unspecified (11) | Phenotypic factors/information (19) |
Using information on medical history (12) | unspecified (5) |
unspecified (6) | referring to gender (4) |
regarding family history (6) | referring to weight (3) |
Using biological information/biomarkers (689) | referring to membership of a certain (ethnic) group (7) |
unspecified (81) | |
of the individual (21) | Personal preferences (4) |
of the disease (13) | Behavior (22) |
on the molecular level (574) | unspecified (8) |
unspecified (101) | referring to nutrition (5) |
information on disease pathways (7) | referring to lifestyle (6) |
referring to toxins (3) | |
D. Usage of (specific) technology (51) | |
Unspecified (17) | |
(New) technology for genetic analysis (30) | |
Information technology (4) | |