Questions and answers | Cases | Controls | P value |
---|---|---|---|
n = 604 | n = 604 | ||
Ethics Committee | |||
1. What is your opinion about the Ethics Committees? | |||
I think most of the time they are aware of what is happening in these studies | 305 (50.5) | 204 (33.8) | < 0.001 |
I am aware they exist but I do not know their function | 133 (22) | 165 (27.3) | |
I do not know what an Ethics Committee is | 111 (18.4) | 127 (21) | |
I am aware that they exist but I am not sure if they fulfill their functions | 45 (7.5) | 56 (9.3) | |
I think most of the time they are not aware of what is happening in these studies | 4 (0.7) | 27 (4.5) | |
I am sure that most of the time they are not responsible of fulfilling their function | 5 (0.8) | 24 (4) | |
Other opinion | 1 (0.2) | 1 (0.2) | |
2. Which is the main function of an Ethics Committee? | |||
To ensure that research physicians and their collaborators are adequately qualified | 180 (29.8) | 192 (31.8) | 0.293 |
I do not know precisely what responsibilities they must fulfill | 175 (29) | 189 (31.3) | |
To review whether the research study characteristics provide benefits to the participants | 87 (14.4) | 63 (10.4) | |
To approve or deny permission to execute a research study | 67 (11.1) | 62 (10.3) | |
To register the experimental drug’s adverse reactions as they occur | 59 (9.8) | 54 (8.9) | |
To interrupt the research study in case they consider that participants could be at risk | 30 (5) | 39 (6.5) | |
To make sure that the informed consent documents are easy to understand | 4 (0.7) | 5 (0.8) | |
Other function | 2 (0.3) | 0 (0) | |
Research studies’ medical care | |||
3. What is your opinion about the research physicians that participate in pharmaceutical industry-sponsored studies? | |||
They must be qualified physicians evaluated by international pharmaceutical companies | 545 (91.3) | 374 (62.1) | < 0.001 |
I have no opinion on the matter because I do not know any research physician | 25 (4.2) | 109 (18.1) | |
They are like any other physician, the only difference is that they do this activity | 20 (3.4) | 67 (11.1) | |
I believe that most of them participate in this kind of studies only because of the money they are paid | 5 (0.8) | 41 (6.8) | |
I think that they must not be very good physicians | 2 (0.3) | 10 (1.7) | |
Other opinion | 0 (0) | 1 (0.2) | |
4. What is your opinion about the medical care that pharmaceutical industry research studies’ participants receive? | |||
It is much better than private medical care | 464 (77.2) | 230 (38.2) | < 0.001 |
It must be the same as private medical care | 81 (13.5) | 157 (26.1) | |
I do not know if it is better or worse than private medical care | 14 (2.3) | 128 (21.3) | |
I believe the most important fact is that the medical care is free of charge | 33 (5.5) | 48 (8) | |
It is inferior to private medical care | 9 (1.5) | 36 (6) | |
Other reason | 0 (0) | 3 (0.5) | |
5. Do you consider that participating in a clinical trial is an adequate way for patients to get medical care | |||
Yes | 599 (99.2) | 537 (88.9) | < 0.001 |
No | 5 (0.8) | 67 (11.1) | |
6. Why do you believe that participating in a clinical trial is an adequate way to get medical care? | |||
Because participants receive closer follow-up than with any other medical center | 308 (51.6) | 175 (32.7) | < 0.001 |
Because participants receive new treatments that offer more advantages than any other medication available | 71 (11.9) | 107 (20) | |
Because international scientists are monitoring the medication’s effects | 93 (15.6) | 79 (14.8) | |
Because these are very strict studies where all medical adverse reactions are monitored | 31 (5.2) | 47 (8.8) | |
Because the physician is available and can be found easily | 53 (8.9) | 23 (4.3) | |
Although it is not ideal, it is the best way to get medical care if you lack economical resources to pay for it | 12 (2) | 51 (9.5) | |
Because they perform a lot of laboratory tests free of charge | 19 (3.2) | 34 (6.4) | |
Because physicians that do medical research are more qualified | 10 (1.7) | 19 (3.6) | |
7. Why do you believe that participating in a clinical trial is not an adequate way to get medical care? | |||
Because of potential risks that are not present when using authorized treatments | 0 (0) | 30 (44.8) | 0.005 |
Because a lot of unnecessary laboratory tests are performed | 1 (16.7) | 16 (23.9) | |
Because treatments are interrupted once the research study is over | 3 (50) | 13 (19.4) | |
Because they require you to assist to a lot of unnecessary consults | 1 (16.7) | 7 (10.4) | |
Did not answered | 1 (16.7) | 0 (0) | |
Other reason | 0 (0) | 1 (1.5) | |
Economical Reimbursement | |||
8. Do you believe that you must receive an economical reimbursement (money) for participating in a research study? | |||
Yes | 299 (49.5) | 321 (53.1) | 0.205 |
No | 305 (50.5) | 283 (46.9) | |
9. What is your opinion about receiving an economical reimbursement (money) for participating in a research study? | |||
There should not be monetary supportive stimuli unless they are strictly justified | 274 (45.4) | 223 (36.9) | < 0.001 |
That it is necessary in order to cover the costs of extra transportation that participating in a study implies | 240 (39.7) | 183 (30.3) | |
I think it is payment for risking my health | 24 (4) | 73 (12.1) | |
Other reason | 17 (2.8) | 36 (6) | |
I think it is a good payment for participating in a research study | 13 (2.2) | 39 (6.5) | |
I think it is used to convince some people to enroll in a research study | 13 (2.2) | 36 (6) | |
Monetary supportive stimuli are not proportionate to the potential risks that participating in a research study implies | 23 (3.8) | 14 (2.3) |